Chennai is located near to tirupathi when compare to other important cities of states. There are 3 best routes from Chennai to Tirupati. The route 1 starts from Chennai to puzhal and goes through nagalapuram and puttur to reach tirupathi. This tirupati trip almost takes 135kms. Route 2 starts from Chennai to tada and goes through srikalahasti and renigunta to reach tirupathi. This route almost takes 150 kms. Route 3 starts from Chennai and crosses thiruvallur, thiruthani and puttur to reach tiupathi. This trip takes almost 155kms. Best recommended way to reach tirupathi is taking Route 1.